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Transcription: [00:06:04]
{SPEAKER name="Hart E. Van Riper"}
And as you know, we've never been able to purify such a solution to eliminate all of the nervous tissue and which nervous tissue is exceedingly toxic to an individual. So, the use of monkey brain or spinal cord as a source of vaccine has been out the window. Now, with tissue culture, we are able to get a pure strain of virus that is free of any contaminant that will be dangerous--at least to the individual. Also, by the tissue culture method, we hope that it may be possible to attenuate this poliovirus. That is, make it less "infecty" for human beings and still retain that part of the virus that produces immunity.

[00:06:49]
{SPEAKER name="Watson Davis"}
Dr. Van Riper, this tissue culture is very interesting because really it's the case of the parts of the human body living after perhaps the original body is dead. And it's a sort of a physiological [[laughter]] immortality, as it were, I think that's [[Cross Talk]] --

{SPEAKER name="Hart E. Van Riper"}
Yes, and it's remarkable the amount of tissue that will reproduce poliovirus. And we're now, another thing, we're trying to standardize tissue culture, that is, to get a group of cells growing that will be the same whether they're used in tissue cultures in Boston or Pittsburgh or San Francisco so that we'll have a standard tissue that the virus is growing on and we'll know exactly what we're dealing with.

[00:07:44]
{SPEAKER name="Watson Davis"}
And you expect to do that in various laboratories or in many laboratories working on that all over the country aren't there Dr. Van Riper?

[00:07:49]
{SPEAKER name="Hart E. Van Riper"}
Yes, there are and then another thing in this matter of an eventual vaccine and we're testing this tissue culture virus with various agents, chemical and physical to determine the best way and means of making them less infective for the human being. I mean after all we cant give a vaccine that will produce disease.

[00:08:12]
{SPEAKER name="Watson Davis"}
Dr. Van Riper someday we hope through the work you're doing and Dr. Salk is doing we will get a prevention for polio and in the mean time the best thing we can do is to take care of those who have the disease and who can in many cases recover and do this very important research which is going on throughout the country and throughout the world.