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52.
ments, it was found that Tropin hydro-chlorate produced vaso-constriction and that sodium tropate gave rise to vaso-dilatation. We have here, then, an important and very decided illustration of the relation of chemical constitution to physiological action and, at the same time, a very striking explanation of the double action of the alkaloid atropin. 
H.G. Beyer. [strikethrough][illegible][/illegible][/strikethrough]. The influence of cocaine on the bloodvessels of the dog not yet published. 
In these experiments, which were made according to the same method as the preceeding, suffice it to state that it was found that cocaine in large doses and directly applied, gives rise to vaso-dilatation, in small doses, to vaso-constriction. - 
[strikethrough] Very Respectfully,Henry G. Beyer [illegible] [/illegible] [/strikethrough]