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13 May

CFES Briefing - Charles Walker (MDAC/STL)

 •"CONVENTIONAL" (l-g) Electrophoresis uses material in a gel, not liquid, since convection & sedimentation make liquid elect. unfeasible. 2 Problems: 1 Size of Convection cells limit diameter of sample stream &; therefore "THROUGHPUT" 2 Gravity induces spreading of stream; therefore sample isn't separated purely

 •Candidates for CFES= Any hormones produced by tissues (Use tissue cultures, + separate out hormones with CFES).
Possible products are:
 Growth Hormones (to aid juvenile bone growth)
 Beta cells (Potential single injection cure for diabetes)
 Alpha-Antitrypsin (Emphesyma)
 Epidermal Growth Cells (Burn Victims)
 Interferon (Viral Infection Immunity)
 Anti-Hemophelic (To prevent immune reactions)

• Samples (~10-25% Solutions) are stored in syringes in a "Refrigerator" (Not freezer), to prevent "Denaturation" of samples... Still good science if refrigerator fails

• The Fluid systems module is actual hardware (with pumps to control the flow, etc). It's powered by orbiter MnB+C, or through the ML86B Galley cb, and has no other orbiter interface.  It comes with its own microprocessor, which sequences, controls, + monitors it - There is no GPC or T/M interface