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31) p. 29. Continued Simple issues. [[left margin]] 1st way recommended. [[/margin]] [[right margin]] The Cause of fluids rising in Capillary Tubes [[/margin]] From what hath been said, it appears, that the certainty of known the effect soon, is one recommendation of the small wound - and giving little, or no pain is another. I have inoculated several sucking children that did not wince, or cry, at all. On the other side, putting it out of our power to know if it has held or not, is the principal objections to large Orifices, and also a hazard of the blood washing away the matter when to large. [[left margin]] Depth & not the length makes the odds. [[/margin]] It is the depth, and not the length, which makes the odds, a scratch of an inch long, if superficial, heals sooner than a puncture of a quarter: An example will prove what is said above. [[left margin]] Examples. of both ways. [[/margin]] About fourteen years ago, two boys and a girl were inoculated in one day, by the latter way. I was sent for the fourth or fifth day to see if it had succeeded: And I found the caddis buried in the wound; the lips inflamed and beginning to suppurate, - but could not say, held or not. They continued mattering a considerable time: During which we were in suspence -- because I had seen some wounds continue with a moist scab upon them full three weeks before the patient sickened, who had a favourable [[strikethrough]] sort [[/strikethrough]] pox and did well. At last all the three healed up without any effect. The parents of the girl then sent her to me, and I gave her the pock in the slight way. At the usual time She sickened and was uneasy for three days; was relieved by a favourable eruption, and lay not an hour longer, and continued well ever since. Have seen others also succeed after once missing. The mother of the two boys had not courage to try again; and both, afterwards died of them in the natural way. Your Magazine, I suppose, goes to [[underlined]] Paris [[/underlined]]. - If [[underlined]] Dr. Gatti [[/underlined]] will be so kind as to acquaint us, whether the Dutchess of [[underlined]] Bouflers [[/underlined]] wounds were large or small, and the rest of the circumstances, he will oblige the public in general, and particularly. A Scots Inoculator. [[right margin]] A Corollary, wherein The [[striketrough]] Cause of liquor [[/strikethrough]] rising ^ [[insertion]] of Liquor [[/insertion]] in Capillary Tubes is accounted for [[/margin]] [[Left margin]] Some Orifices enlarge & others not [[/margin]] P.S. Sometimes the orifices for inoculation enlarges to a little Ulcer, nay, I have heard of them, but never saw any, continue running sores. This has been imputed to their being too large at first; to me it seems mostly, if not altogether to depend on the habit of body. [[left margin]] Example. [[/margin]] I inoculated two sisters at the one time, exactly in the same gentle way, one of the openings spread till it could receive two or three peas; and only healed by the help of a little calomel. The other could scarce admit of half a pea, and in many others have seen the smallest rasure enlarge greatly, and a large orifice not widen at all. [[left margin]] No. of the pox [[/margin]] The numbers of the pox after inoculation seems also to depend upon the constitution, and neither on the bigness nor smallness of the wound, nor on the quantity of matter applied, a very great load being some times (Continued on p. 33)